In the Richardson Cup, holders Tempest United will play near neighbours CMB while Rossendale - the only non Premier Division side left in the competition - face Slyne with Hest.
In the Presidents Cup semi-finals, last year's beaten finalists Haslingden St Mary's will need to bypass Eagley to reach the final again.
The winners of the quarter-final tie between Milnthorpe Corinthians and Thornton Cleveleys will be met by Poulton in the semi-final.
And in the Challenge Cup, we have a Cumbrian derby between Kendal County and Dalton United while Carnforth Rangers meet Hesketh Bank.
All ties will be played at 3pm on April 1 and venues to be announced.
Miller Roskell Limited Richardson Cup Semi-Final
Tempest Utd v CMB
Slyne with Hest v Rossendale
Presidents Cup Semi-Final
Eagley v Haslingden SM
Miln Cor / T Cleve v Poulton
Challenge Cup Semi-Final
Kendal Co v Dalton Utd
Carnforth Rgrs v Hesketh Bank
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